New Biologically Active Compounds from the Nematode-Trappmg Fungus Arthvobotrys oligospora Fresen

نویسندگان

  • Marc Stadler
  • Heidrun Anke
چکیده

The isolation, structural elucidation and biological activities of oligosporon (1), oligosporol A (2) and oligosporol B (3), three new antibiotics from cultures of the predacious deuteromycete, Arthrobotrys oligospora, are reported. The structures were elucidated by means of high resolution mass and high field N M R spectroscopy. The compounds exhibited weak antimicro­ bial, cytotoxic and hemolytic effects, but were not active towards the nematode Caenorhabditis elegans. Other Arthrobotrys species were also found to produce these or similar compounds.

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تاریخ انتشار 2013